AMBAR MUDIGDO

BIOLOGI MOLEKULERMempelajari berbagai aspek kehidupan pada level sub sel.

Memahami dasar-dasar molekuler yang menentukan sifat fenomena biologis (misal : reaksi kimia dalam sel)

ASPEK KEHIDUPAN SOSIAL EKONOMI BUDAYA PENDIDIKAN HUKUM KESEHATAN DLL

KESEHATAN PROMOTIF PREVENTIF DIAGNOSIS CURATIF REHABILITASI

BIOLOGI MOLEKULERVisi Pendidikan Dokter / Dr.Spesialis berubah

Ekosistem berubah : Geografis Lingkungan Sosial Ekonomi Budaya Hankam

BIOLOGI MOLEKULER

Paradigma baruPenelitianPatogenesis dan patofisiologi baruKonsep dan teori baruAplikasi lebih efektif dan efisien

Smart & beautiful mindStep on calculated risk

- How to get an added value- From teoritical concept to practical applied

COPING MECHANISM STRESSOR JARINGAN TUBUH REAKSI ADAPTASI ALARM EXHAUST MANAJEMEN STRESSOR :- POSITIF- NEGATIF

WHOLE BODY

SYSTEM

ORGAN

TISSUE

CELL

SUB CELLCHROM.GENEDNA , RNA , PROT

NO CLINMANIFESTCLIN PROBLEM

DIAGNOSISSUB CELL / GENETIC LESSION : MOLECULERCELL LESSION: SITOLOGITISSUE LESSION: HISTO PATOLOGI ANATOMI CT SCAN , USG, MRIORGAN LESSION: CT SCAN , CLINICAL Dx

BIOLOGI MOLEKULERCancerMetabolic DiseaseGenetic lesionDegeneratifAging process

METABOLIC DISEASEDiabetes MelitusOral anti DiabeticInsulin

Pre insulinPro insulinInsulin

Sub sel levelMitochondriaFe, Gluthation, Glycin, Antioxidant

Kanker :multifactor: Instrinsic Ektrinsic

Multi Hit: akumulasi lesi genetik

Multi Step: Inisiasi Promosi Progressi

NINTC.PROMPMEX.PROGMMASSCOMP : -LUMENDISTR -VASA. NINFIL T. OR

META

PROMOTINGINHIBITING

ONKOGENTUM.SUP .GAPOP/PCD.GDNA REPAIR G.HOMEOSTATIS BALANCE

IMBALANCE: - MUTATION - MULTIPLICATION - DEGRADATION

INTRINSIC: - HER./ GENE LESION- HORMONAL- METABOLICEXTRINSIC:MICRO ORG :NUTRIT:METAB:TOXIC / CHEM :

TUMOR CELLS NOT DEPENDENT ON .GF. NOT COORD. GROWTH LESS ADHESIVE NON STOP GROWING PURPUS

Clinical manifestasionCell / tissue lesionSub cell / genetic lesion

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