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Write these terms and their meanings in your notes related to the Integumentary System. EPIDERMIS (epi- = upon/over) DERMIS (derm- = skin) (SUBCUTANEOUS OR SUPERFICIAL FASCIA) This is not considered the “true” skin or integument. HYPODERMIS (hypo- = below)(sub-=below)(cutane-=skin) *Also, write the standard on the following slide in your notes. Bell Work for Day One

Bell Work for Day One...does the integument (skin) provide protection? Temperature maintenance-Think about your own body…what happens when you get too hot? Too cold? Synthesis and

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  • Write these terms and their meanings in your notes related to the Integumentary System.

    EPIDERMIS (epi- = upon/over)

    DERMIS (derm- = skin)

    (SUBCUTANEOUS OR SUPERFICIAL FASCIA) This is not considered the “true” skin or integument.

    HYPODERMIS (hypo- = below)(sub-=below)(cutane-=skin)

    *Also, write the standard on the following slide in your notes.

    Bell Work for Day One

  • THE INTEGUMENTARY

    SYSTEM-

    THE LARGEST ORGAN

    Anatomy & Physiology

  • 8) Create a model with a written, digital, or verbal explanation of the three layers of skin (epidermis, dermis, and subcutaneous). Summarize functions and characteristics of each layer; describe layers within epidermis and dermis; outline and sketch cell types and definitions, appendages, blood supply, innervation, and possible lesions.

    Standard-(write in your notes)

  • Outline the structure and function of the three layers of the skin (including its appendages, nerves, and blood vessels) through the creation of a model.

    Distinguish each cell type of the skin by outlining a provided sketch.

    Objectives for Day One

  • The Integumentary System

    2 components of the integumentary system:

    1. Cutaneous membrane Epidermis

    Dermis

    Hypodermis

    2. Accessory structures (appendages)

    Hair

    Nails

    Exocrine glands

    Consider previous classes, how are exocrineglands different than endocrine glands?

  • Functions of the Integumentary System

    Protection- Consider past lessons…In what ways does the integument (skin) provide protection?

    Temperature maintenance- Think about your own body…what happens when you get too hot? Too cold?

    Synthesis and storage of nutrients- We will discuss these later in this lesson, but what other body system would the integument communicate with based on this function?

    Sensory reception – What body system does this relate to? Which special sense relates to the integument?

    Absorption- What is an example of something the integument absorbs?

    Excretion & secretion- What do these mean?

  • What is excretion? What is secretion?

    What’s the difference? Write examples of each in your notes. (Make sure you know the difference!)

    Quickly view the link explaining the differences:

    http://www.differencebetween.net/language/words-language/difference-between-excretion-and-secretion/

    Share out!

    http://www.differencebetween.net/language/words-language/difference-between-excretion-and-secretion/

  • Epidermis

    Superficial epithelium

    Avascular- What does this mean?

    Thick skin – 5 layers

    Palms of hands, soles of feet

    Thin skin – 4 layers

    Layers of epidermis:

    1. Stratum basale

    2. (Intermediate strata)

    1. Stratum spinosum

    2. Stratum granulosum

    3. Stratum lucidum- (only hands/feet)

    3. Stratum corneum

    **Broccoli Soup Gives Lucy Cramps!

  • Stratum Basale (start at the base)

    Epidermal ridges extend downward into the dermis

    Dermal papillae extend upward between epidermal ridges

    Ridge contours are genetically determined

    **This combination yields our fingerprints!!!

    Obtains nutrients from dermis (Is this excretion or secretion?)

    Composed mostly of stem cells (continuous cell division occurs here)

    Contains melanocytes

  • Intermediate Strata (3 layers)

    Stratum spinosum

    Spiny layer

    Continues cell division

    Stratum granulosum

    Grainy layer

    No cell division

    Produces keratin Protein, water-resistant & durable

    *Stratum lucidum

    Flattened & densely packed

    Filled with keratin

    Only found in thick skin

    *(Palms of hands and soles of feet)

  • Stratum Corneum

    Most superficial layer

    15-30 layers

    Cells are dead & keratinized

    Tightly connected and flat

    Cells are shed after ~2 weeks

    (Activity: Take 3-5 minutes, draw a

    sample of the diagram to the right,

    outlining the cell types in each layer.)

  • Thick Skin

  • Thin Skin

  • Skin Color - Pigmentation

    Carotene – orange/yellow pigment

    Converted to vitamin A, which maintains epidermis

    Melanin – brown/yellow/black pigment

    Made by melanocytes in the stratum basale

    Stored in intracellular vesicles

    Production increases with UV light What do we call this?

    Melanin absorbs UV radiation to prevent burns

    Freckles are areas with heavy melanin production

    Dermal Circulation

    Gives skin reddish color due to blood vessels in the dermis

    What happens if melanin is NOT produced at all?

  • Melanocytes

  • Albinism Vitiligo

    Albinism:

    Absence of melanin

    Vitiligo:

    Melanin

    cells die

    or stop

    functioning

  • The Sun

    Vitamin D3 is synthesized in the stratum spinosum and stratum basale after UV exposure

    Not enough Vitamin D3 = abnormal bone growth

    Too much Vitamin D3 = premature wrinkling(damaged connective tissue), chromosome damage (skin cancer)

    Is the sun the only cause for wrinkling or cancer?

  • Dermis

    Lies beneath epidermis

    2 major layers

    1. Papillary layer

    loose connective tissue

    Support & nourishment

    Contains capillaries and nerves that supply the epidermis

    2. Reticular layer

    Dense irregular connective tissue

    Elastic fibers provide flexibility, collagen fibers prevent damage from flexibility

    Contains blood vessels, nerve receptors, hair follicles, and sweat glands

  • Nerve Receptors (Innervation)

  • Hypodermis

    AKA subcutaneous layer

    Not part of “true” integument

    No clear distinction between hypodermis & dermis

    Loose connective tissue with many adipocytes-

    What types of cells are these?

    Functions:

    Reduces heat loss

    Energy reserve

    Absorbs shock

    Accumulates differently in males & females

    Elastic

    No vital organs, few capillaries

    Good for subcutaneous injections with a hypodermic needle

  • Accessory Structures - Hair

    Everywhere except sides & soles of feet, palms of hands, sides of fingers & toes, lips, & parts of external genital organs

    Hair follicles: produce hair

    Structure:

    Follicles project into dermis and hypodermis

    Follicle contains cells of epidermis

    Hair papilla – peg of connective tissue containing capillaries & nerves

    Hair root – anchors hair to skin

    Hair shaft – 3 layers of dead, keratinized cells1. Cuticle – surface layer of hair, overlapping shingle-like cells

    2. Cortex – underneath the cuticle

    3. Medulla – core of the hair, underneath the cortex

  • Accessory Structures - Hair

  • Accessory Structures - Hair

    2.5 million hairs on the human body!

    ~500,000 on the head

    Functions of hair:

    UV protection

    Cushioning (head)

    Insulation

    Prevents entry of foreign particles into nostrils, ears, and eyes What hair protects our eyes?

    Prevents injury

    Sensory nerve fibers can feel movement of the hair shaft

    Responds to stress, cold, or anger/fear

    Arrector pili muscles in the dermis force hair to stand up

  • Accessory Structures – Hair (Color)

    Differences in hair color due to amount of pigment

    produced by melanocytes

    Genetically determined

    Eumelanin-dark

    Pheomelanin-light

    No pigment or presence

    of bubbles-gray/white

    Share out!

    What makes a person’s hair straight or curly?

  • Accessory Structures – Sebaceous Glands

    Holocrine glands- Arrector pili muscle contracts and squeezes oil out of the gland…This oil is called…

    Sebum – oily secretion

    Lubricates hair & skin

    Inhibits bacteria growth

    What was one of our first lines of defense in the immune response?

    Sensitive to changes in sex hormones

    Acne caused by blocked sebaceous ducts

    Secretions accumulate and become inflamed

    May lead to bacterial infection

  • Accessory Structures –

    Sudoriferous (Sweat) Glands

    Apocrine sweat glands

    Secrete products into hair follicles in armpits, around nipples, and groin

    Sticky, cloudy secretion released at puberty

    Becomes odorous when bacteria break it down (food source)

    Merocrine sweat glands

    coiled tubular glands

    Discharge secretions directly onto skin surface

    Most numerous in palms of hands and soles of feet

    99% water plus electrolytes, organic nutrients, & waste

    Cools skin surface & lowers body temperature

    Too much perspiration = dehydration

    Flushes microorganisms from the surface-line of defense!

  • Sweat Glands

    Think.Paire.Share.

    What are examples of

    times we sweat?

    What is the cause?

    What body systems

    relate to the structure

    and functions of these

    glands?

  • Accessory Structures - Nails

    Protect finger tips & limit distortion when exposed to mechanical stress

    Nail body – dead keratinized cells

    Visible part

    Nail bed – epidermis covered by nail body

    Nail root – site of nail production

    Cuticle – portion of the stratum corneum extending over the nail

    Lunula – pale crescent

    Blood vessels obscured

  • Group Activity

    Create a 3D Model of the Integumentary System. Label the

    layers and their components, nerves, hairs, and sweat glands.

    On a separate sheet of piece, write down the functions of each

    layer.

    These will be judged and the winners will receives 2 points on

    any test!

  • “Can’t touch this!” End of class activities….

    Exit Ticket:

    Without looking at your notes, summarize the

    functions of each layer of the integumentary system.

  • Bell Work Day Two

    What are the names of the two types of glands we

    discussed yesterday?

    Research two more types of glands found in the

    integumentary system: Ceruminous glands and

    Mammary glands.

    1. What are the functions of each?

    2. Can any problems occur with these glands?

  • Standards for Day Two

    8) Create a model with a written, digital, or verbal

    explanation of the three layers of skin (epidermis,

    dermis, and subcutaneous). Summarize functions and

    characteristics of each layer; describe layers within

    epidermis and dermis; outline and sketch cell types

    and definitions, appendages, blood supply,

    innervation, and possible lesions.

  • Objectives for Day Two

    Briefly review yesterday’s material.

    Sketch and describe possible skin lesions and the layers of skin affected.

    Continue 3D Model Group Project of the Integumentary System.

    “Crash Course” review with guided notes.

    https://www.youtube.com/watch?v=Orumw-PyNjw

    https://www.youtube.com/watch?v=Orumw-PyNjw

  • Draw a sketch and describe each!!(Page 76-77 in the small Body Structures and Functions book.)

    Describe the various lesions of the skin:

    Bulla (large blister)

    (called a bleb if on lung)

    Macule (freckle)

    Nodule (wart)

    Pustule (pimple, acne)

    Differentiated between the depth,

    circumference, pus, or fluid.

    Papule (mole, birth mark)

    Tumor (benign or not)

    Vesicle (small blister)

    Wheal (hives, insect bite)

  • This chart has a few

    more examples along

    with visual

    representation.

    Think.Pair.Share.

    Notice the scar.

    Do you have any

    scars?

    What are some

    examples of scars?

    Do they all look the

    same?

    Are they all due to

    injury?

  • How about these?

    What are some other examples?

    Fissure (Crack or Split)

  • Acne Vulgaris

    Common chronic disorder of the sebaceous glands

    Due to excess production of oil

    Plugs the opening to the gland preventing outflow of oil

    White blood cells attack creating pus and an inflammatory response.

    What body system does this relate to?

    Can lead to cellulitis (an infection of the subcutaneous layer of the skin)

    What is the oil called that is produced?

    Applying what you know about infection

    control, what might be a cause of cellulitis or

    other skin infections?

  • …Continue with Group Project

    Create a 3D Model of the Integumentary System. Label the

    layers and their components, nerves, hairs, and sweat glands.

    Add to your model at least three different lesions!!

    On a separate sheet of piece, write down the functions of each

    layer.

    These will be judged and the winners will receives 2 points on

    any test!

  • Exit Ticket

    What is an example of a wheal?

    What is the term for a large blister located on the

    lungs?

    Acne Vulgaris is a chronic disorder of (sebaceous

    OR sudoriferous) glands?

    A macule lesion is what we normally refer to as a

    (mole OR freckle)?

  • Bell Work Day Three

    What other body systems relate to the

    Integumentary System?

    How?

    Copy the new standard (9) in your notes.

  • Standards for Day Three

    (write the new one in your notes)

    8) Create a model with a written, digital, or verbal explanation of the

    three layers of skin (epidermis, dermis, and subcutaneous). Summarize

    functions and characteristics of each layer; describe layers within epidermis

    and dermis; outline and sketch cell types and definitions, appendages,

    blood supply, innervation, and possible lesions.

    9) Investigate and obtain information on a skin disorder/disease/syndrome

    from a medical/healthcare journal or textbook. Appraise a sample case

    study involving review of the A&P of the cells and tissues affected. Decide

    whether an inflammatory response was involved, identify the causative

    agent, locate signs and symptoms of the disorder, and relate to normal

    A&P.

  • Objectives Day Three

    Investigate various diseases and disorders

    associated with the integumentary system.

    Work with a small group to research an assigned

    disease/disorder and create a PowerPoint to

    present to the class.

  • Inflammatory Skin Diseases

    Dry red itchy scaly appearance to the skin

    Mainly due to an underlying allergic reaction

    Avoidance of the cause typically cures

    Non-contagious

    Dry reddish patches covered with silvery white scales.

    Typically seen on elbows, knees, scalp and back

    Treated using immune system suppressing drugs.

    Genetic

    Eczema Psoriasis

  • Acute vs. Chronic

    Eczema (Acute) Psoriasis (Chronic)

  • Boils

    Painful bacterial infection of the hair follicles or sebaceous glands

    Typically due to a staph infection.

    Deep in the skin and often require drainage, excision, and antibiotics

    **Warning: yucky picture ahead**

  • Drainage of a Boil

  • Skin Repair

    Skin is easily regenerated due to stem cells

    Inflammatory response – triggered by mast cells to

    increase blood flow

    Scab restricts entry of microorganisms

    Cells of the stratum basale rapidly divide to replace lost cells

    Macrophages & phagocytes clear away debris/pathogens

    Scar tissue – collagen fibers with few blood vessel

    Keloids – thickened scar tissue with shiny smooth surface

    Damaged hair follicles, sebaceous & sweat glands,

    muscle cells, and nerves are rarely repaired

  • Aging

    Epidermis thins as stem cell activity decreases

    Higher risk of skin injury and infections

    Skin tears (thin like paper)

    Number of macrophages & other immune system cells decrease

    Decline in Vitamin D3 weakens muscles & bones

    Melanocyte activity decreases causing increased sun sensitivity

    Gland activity decreases causing dry/scaly skin

    Follicles decrease function creating thinner hair

    Elastic fibers decrease causing wrinkling

    Less blood supply to dermis means less thermoregulation

    What does that mean??

    Repairs are very slow

    3-4 weeks in young adults = 6-8 weeks at ages 65-75

    Causes recurrent infections

  • Think.Pair.Share.

    The cosmetic industry sells many products claiming to

    remove or prevent wrinkles. If this is true, why do

    people who use these creams still wrinkle as they

    age?

    What are simple ways to maintain healthy skin even

    with aging?

  • Group Project: Research and PPT

    Burns

    Skin Cancer

    Decubitus Ulcers

    Diabetic Wounds

    Click on the link from

    the website titled

    Group Project

    Assignments.

    Follow the instructions

    carefully.

    Each group has

    specific instructions.

  • Individual Activity

    Click the link called The Long and Short of Nails.

    OR https://cookhealthscience.weebly.com/uploads/1/3/0/8/13084909/fingernails_related_to_

    disease_and_disorder.pdf

    Summarize your findings.

    Copy the descriptions and related conditions in your

    notes.

    https://cookhealthscience.weebly.com/uploads/1/3/0/8/13084909/fingernails_related_to_disease_and_disorder.pdf

  • Exit Ticket

    What are three examples of signs or symptoms that

    the skin has been compromised and may require

    specific treatment.

    Why is it important to pay close attention and care

    for your own skin?

  • Bell Work Day Four

    Answer the 5 review questions on page 76 in the

    small Body Systems book.

    Then go to work on your projects!!!

  • Bell Work Day 5

    Define the following from your small Body Systems

    book (page 73):

    Shingles (herpes roster)

    Herpes simplex

    Genital herpes

    Impetigo

    Ringworm

  • Activities

    Present projects.

    Read Burn Injury Case Study and complete the

    questions.

    (You may use your textbooks and internet sources to

    help answer the questions).