1. Pharmacodynamics IV
Spring 2011
Acute Myocardial Infarction
Kyoungmin Lee
Angela Paul
Cory Phillips
Jaime Tausend
Sonia Tadjalli

2. Introduction
Occlusion of a coronary artery
Death of cardiac myocyte
Wide range of clinical sequelae
Result in cardiogenic shock and death
About 1.5 million people experience MI
3. Risk Factors
Age
Gender (male)
Dyslipidemia
Diabetes
Hypertension
Obesity
Lack of physical activity
Alcohol overconsumption
Tobacco use
Family history of atherosclerotic disease
4. Pathophysiology
Atherosclerosis
Plaque rupturing
Thrombus formation
Adhesion
Activation
Aggregation
5. Presentation

Common symptoms:

6. Chest pain associated with tightness or squeezing 7. Pain in the arms and/or upper back 8. Upper abdominal discomfort 9. Jaw pain, toothache, and/or headache 10. Dyspnea 11. Diaphoresis 12. Malaise 13. Women are more likely to experience an atypical MI 14. Some patients may not experience any symptoms are known as a silent heart attack