Acanthamoeba Keratitis; A Clearer Vision for the Future .Acanthamoeba Keratitis; A Clearer Vision

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Text of Acanthamoeba Keratitis; A Clearer Vision for the Future .Acanthamoeba Keratitis; A Clearer Vision

  • Acanthamoeba Keratitis;

    A Clearer Vision for the

    Future

    Professor John Coia and Dr. Claire Alexander

    Scottish Parasite Diagnostic and Reference Laboratory

    Glasgow Royal Infirmary

  • Caused by Acanthamoeba species

    Associated with contact lens use

    3.7 million contact lens wearers in

    the UK

    Incidence in Scotland 149 cases per

    million?

    Acanthamoeba Keratitis

  • Daily Mail May 2015:

    A parasite from my contact lens is gnawing into my eyeball: The

    gruesome truth about a scarily common bug.

    Metro Newspaper Oct 2015:

    Woman nearly has her eye eaten from the inside by horrible

    parasite..

    Recent Media Awareness

  • Early phase responds to antimicrobials

    Advanced phase requires surgery

    Clinical Presentation

  • Issues

    Symptoms

    mimic

    other diseases

    Inaccurate

    diagnosis

    Inappropriate

    treatment

    Significant

    NHS costs

    Ineffective

    laboratory

    testing

    Delayed

    diagnosis /

    Poor prognosis

  • STEP 2

    Explore

    Testing

    Options

    STEP 3

    Engage

    with

    Reference

    Lab Staff

    STEP 4

    Develop

    Assay

    STEP 5

    Implement

    STEP 1

    Engage

    with users

    & HPS

    What Next?

  • ReviewAudit

    Phone positive findings

    AdaptPatient information

    leaflet

    Staff sampling leaflet

    Collection tubes

    ShareWorkshops

    Training others

    Update

    NetworkLocal, national,

    international meetings

    Sustainable Commitment

  • Improvements

    Improved quality of patient care

    Significant cost savings

    Improved epidemiological data

    Greater awareness and understanding of the disease

  • UK-wide testing

    In-depth molecular profiling

    Inclusion of other ocular pathogens

    Vision for Future

  • Team photo!

  • Scottish Microbiology Reference Laboratories, Glasgow

    Diagnostic Directorate, Greater Glasgow and Clyde NHS

    Health Protection Scotland

    Scottish NHS Ophthalmology Departments and Microbiology

    Laboratories

    Scottish Virology Microbiology Network

    Funding support was provided through NHS National Services Scotland

    Acknowledgements