8th International Symposium on OMICS and 2018. 9. 11.¢  Targeting protein hydrophilic regions by MS

  • View
    0

  • Download
    0

Embed Size (px)

Text of 8th International Symposium on OMICS and 2018. 9. 11.¢  Targeting protein hydrophilic...

  • 8th International Symposium on OMICS

    and Bioinformatics

    September 17 to 20, 2018

    Melia Marina Varadero Hotel, Cuba

  • Index OPENING SESSION ...................................................................................................... 1

    Monday September, 17th ...................................................................................... 1

    ORAL PRESENTATIONS ................................................................................................ 2

    Tuesday September, 18th ....................................................................................... 2

    Wednesday, September 19th ................................................................................ 4

    Thursday, September 20th ...................................................................................... 6

    ORAL SESSION ABSTRACTS ......................................................................................... 7

    Integration and translation of “omics technologies” to develop personalized

    medicine ................................................................................................................ 9

    TB or not TB: New metabolomics biomarkers better characterizing and

    diagnosing tuberculosis. ...................................................................................... 11

    Advances and Challenges of Single Cell RNA Sequencing Data Analysis .............. 14

    Natural antisense transcripts, physiological roles and potential biomedical

    applications .......................................................................................................... 15

    Past and present of laser capture microdissection application in intracardiac

    nervous system research ..................................................................................... 16

    Imaging mass spectrometry and microbial metabolomics on track of infectious

    diseases ................................................................................................................ 17

    Ambient ionization mass spectrometry in bioanalysis ......................................... 19

    Advanced molecular tools for parallel protein analyses, imaging and diagnostics

    ............................................................................................................................. 20

    Personalised Medicine: the Application of Genomics to Health Care ................. 21

    Novel Atxn2-CAG100-KnockIn mice as model of Spinocerebellar Ataxia type 2 .. 22

  • Metabolome and lipid profile of SCA2 brain tissue in Atxn2-CAG100-KnockIn

    mice and in a patient ........................................................................................... 23

    Modulation of genes for the combination phycocyanobilin and ifn beta promises

    greater expectations for a new therapy for multiple sclerosis ............................ 25

    HLA alleles and TNF promotor genes polymorphism among Cuban patients group

    with MS and NMO................................................................................................ 27

    Assessment of variants in the huge Titin gene - NGS results in 2700 myopathy

    patients ................................................................................................................ 29

    Global analysis of genes expression regulation by the antitumor peptide CIGB-

    300 in acute myeloid leukemia cell lines ............................................................. 32

    Variety of proteoforms in cancer cells ................................................................. 33

    Nutriepigenomics in Cancer Development .......................................................... 35

    POSTER SESSION ....................................................................................................... 36

    POSTER SESSION ABSTRACTS .................................................................................... 40

    Pilot study: Study of utility of depressive symptom screening through

    measurement of saliva biomarker ....................................................................... 42

    Decreased Quality of life in Elderly Patients with Subsyndromal Depression ..... 44

    Salivary cortisol level in sleep-disordered breathing patients ............................. 46

    Antidepressants and Mood Stabilizers: Novel Research Avenues and Clinical

    Insights for Bipolar Depression. ........................................................................... 48

    Associations between immune activation and the current severity of the "with

    anxious distress" specifier in patients with depressive disorders ........................ 50

    There is a correlation between plasma erythropoietin levels and attention deficit

    hyperactivity disorder symptoms ........................................................................ 52

    Plasma glial-derived neurotrophic factor in attention deficit hyperactivity

    disorder ................................................................................................................ 54

  • Korean Medication Algorithm for Bipolar Disorder: changes in preferred

    medications for mania over 16 years ................................................................... 56

    Association Study between Amisulpride Treatment Response and Dopamine D3

    Receptor Gene Polymorphisms in schizophrenic patients ................................... 58

    Effects of LY341495 on the dendritic outgrowth and spine formation in the rat

    hippocampal neuron under toxic condition ......................................................... 60

    Association between glycogen synthase kinase-3β gene polymorphisms and

    attention deficit hyperactivity disorder in Korean children: A preliminary study 62

    A case-control association study of serotonin 1A receptor gene and tryptophan

    hydroxylase 2 gene in attention deficit hyperactivity disorder. ........................... 64

    Increased levels of plasma brain-derived neurotrophic factor (BDNF) in children

    with attention deficit-hyperactivity disorder (ADHD) .......................................... 66

    Liraglutide activates mTORC1 signaling and AMPA receptors in rat hippocampal

    neurons under toxic conditions ........................................................................... 67

    Interaction of TNF-alpha (-308 GA) polymorphism and HLA-DRB1/DQA1 alleles

    associated with susceptibility to multiple sclerosis. ............................................ 69

    Comparative study of gene expression in the colon of rat biomodel with

    ulcerative colitis, treated or not with Pellet-EGF. ................................................ 71

    Expression profile of genes related to apoptosis in the colon of rats with

    ulcerative colitis treated with EGF ....................................................................... 73

    Identification of the reference materials proteins from Saccharomyces cerevisiae

    by 2DE and Mass Spectrometry ........................................................................... 74

    Characterization of low‐abundance species in the active pharmaceutical

    ingredient of a synthetic peptide CIGB‐300 ......................................................... 75

    Targeting protein hydrophilic regions by MS via in-solution buffer-free trypsin

    digestion .............................................................................................................. 76

    In Silico Assessment of Potential Druggable Pockets on the Surface of

    Nucleophosmin .................................................................................................... 77

  • In silico analysis of the interaction between the HLA II receptor associated with

    Reumetoid Arthritis and altered peptide ligand. ................................................. 78

    Impact of post-translational modifications on signaling pathways in patients with

    lung cancer ........................................................................................................... 79

    CIMABior® a cuban human anti-CD20 monoclonal antibody to patients with

    indolent non-Hodgkin lymphoma. ........................... ¡Error! Marcador no definido.

    HLA alleles and TNF promotor genes polymorphism among Cuban patients group

    with MS and NMO.................................................... ¡Error! Marcador no definido.

    Analysis of post-translational modifications in Acute Myeloid Leukemia and their

    impact in the discovery of new biomarkers. ........................................................ 80

    Mass Spectrometric analysis and biological activity of Bm86-pP0: A peptide-

    conjugated vaccine candidate against ticks ............. ¡Error! Marcador no definido.

    PARTICIPANTS LIST.................................................................................................... 82

    Convention Center Maps .......................................................................................... 90

  • 1

    OPENING SESSION (Hicacos II room)

    Monday September, 17th

    18:00-18:15 Welcome remarks:

    Dr. Silvio Perea, Cuba (Center for Genetic

    Engineering and Biotechnology, Havana, Cu