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5.3 GENES & CHROMOSOMES

5.3 Genes and Chromosomes

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Biology Form 5Chapter 5 : Inheritance

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5.3 GENES & CHROMOSOMES

1

CHROMOSOMES

Found in nucleus

Consists of two chromatids that are joined at the centromere

Contain inheritable genetic material that is passed down from parents to progeny

GENES

Gene : a section of DNA

Gene : Each gene controls the synthesis of a protein

Each chromosome consists of a series of genes

DNA

Deoxyribonucleic Acid

Formed from basic units that are called nucleotides

Each nucleotide consists of :

Deoxyribose sugar

Organic nitrogen base

Phosphate Group

DNA Replication

Application of Genetic Knowledge in Life

Agriculture, Medicine

The contribution of genetic research is carried out through:

Selective Breeding

Genetic engineering

DNA FINGERPRINTING

DNA fingerprinting

A discovery in the field of genetics can be used for determining the identity of an individual

Usage:

Solve criminal case

Determining / identifying the parents of a child

Detection of diseases such as cancer, viral or genetic diseases

Blood, hair, skin, semen obtained from the scene of a crime

DNA is extracted from these samples

A specific enzyme acts on the DNA molecule that is long breaking it up into smaller fragments

The DNA fragments of different sizes are separated and arranged according to size

An alkali is added and the double-stranded DNA is separated into single strands. The single strand is then transferred to a nylon

membrane

Radioactive matter is added to the single strand. A banding pattern

appears

An X-ray film is produced and this shows the positions of the dark bands which compared with the part DNA that was

Human Genome Project

Benefits:

Genes that cause inherited disease can be identified

Genetic diseases can be studied

Diseases that are caused by the interaction of genes with the environment can be studied

The actual treatment for a disease can be identified

Genetic engineering

Scientific manipulation of genes & chromosomes in living cells of an organism

Allows good gene to be introduced into parental cells & genes for undesirable traits can be remove

Genetically Modified Food

AdvantagesDisadvantagesSolving the problem of shortage of food Human health might be affectedProduction of crops & livestock that are more nutritiousPossibility of biodiversity being affectedProduction of crops that do not require the use of pesticidesContent of human DNA can be affectedProduction of edible vaccine that can result in the reduction of infectious diseasesTechnology can be misused by developed countries through the production of huge quantities of GMF so that these developed countries can have economic control over the less developed countriesProduction of foods that are tastier & more easily digestedGMF technology is seemingly going against nature

Selective Breeding

Involves producing new generations of crops & livestock that possess desirable characteristics through cross breeding of high quality parents

Benefits:

A shorter maturity time

Improve quality & quantity

Hybrids are better adapted to local climate

Resistance of hybrids to the spread of diseases

Qualities of the psifera variety:

Desirable:

high oil content

ndesirable:

shell-less fruit

fruit drops off before maturity

seeds are difficult to germinate

Qualities of the dura variety:

Desirable:

does not have the weaknesses of psifera

Undesirable:

low oil content

Crossing psifera with dura produces the tenera

Qualities of the hybrid tenera:

thin shell

high oil content

bears fruit much faster

larger fruits

palm tree is not too high

fruit does not drop before maturity