PATENT ABSTRACTS

isoenzyme are located in different zones of the element. The isoenzym¢ is present in one of the zones in an amount of at least about 100 I.U./m2. This level of isoenzyme reduces or eliminates bias caused by endogenous alkaline phosphatase and hemoglobin during an assay.

4806484

P E R F U S I O N A I R L I F T B I O R E A C T O R

Asho Petrossian, Andy DeGiovanni assigned to IGB Products Ltd

A perfusion airlift bioreactor system that con- sists of the bioreactor, a media reservoir and a molecular weight cutoff (MWCO) filter positioned between the media reservoir and the airlift bioreactor.

275

A method of making an electrophoresis sheet composed of two sheet members formed of a non-conductive organic polymer film and dis- posed to stand facing each other, spacers having predetermined thicknesses disposed at both edge portions between the two sheet members, and an electrophoresis gel membrane of uniform thick- ness provided with slots extending from an upper edge portion towards a center and grasped bet- ween the two sheet members, comprises the step of forming the slots by pushing a cutting blade member against a gel membrane web before the gel membrane web is grasped between the sheet members. The cutting blade member is com- posed of a combination of a single linear trans- verse blade having a plurality of cutaway portions and disposed to extend in a transverse direction of the gel membrane web, with a plurality of linear longitudinal blades continuing to the linear transverse blade at both ends of each of the cutaway portions.

4810183

A P P A R A T U S F O R C A S T I N G T H I N L A Y E R G E L M E D I A I N A M O U L D

A N D S U B S E Q U E N T L Y U S I N G G E L F O R E L E C T R O P H O R E T I C

S E P A R A T I O N W I T H O U T R E M O V I N G I T F R O M T H E

M O U L D

John F Place, Andre Bregnard, Geneva, Switzer- land assigned to lntraCel Corporation

A mould for the casting of thin, cross-linked, polymerized resin films is subjected, when being filled with the liquid to be polymerized, to a cen- trifugal force field exceeding that of the earth gravitation field, the whole being for equalizing the intimate structure of the polymer and to ex- pel therefrom the bubbles of gas possibly present therein. After curing the gel, a mixture of com- pounds to be separated by the application of an electric field is introduced into the gel and the lat- ter is subjected to electrophoresis within the mould itself.

4810341

M E T H O D O F M A K I N G E L E C T R O P H O R E S I S S H E E T

Sigeru Tezuka, Saitama, Japan assigned to Fuji Photo Film Co Ltd

4810630

U S E O F P O L Y O X Y E T H Y L E N E E T H E R S T O I M P R O V E T H E

P E R F O R M A N C E O F I M M U N O A S S A Y S E M P L O Y I N G

P E R O X I D A S E C O N J U G A T E S

Alan Craig, Thomas P Hartz assigned to E I Du Pont de Nemours and Company

Signal to noise ratio of enzyme immunoassays employing peroxidase conjugates can be im- proved by including polyoxyethylene ether detergent in the assay buffer. Such detergents reduce interference due to blood and also im- prove sensitivity of assays of blood-free samples.

4810631

S I G N A L E N H A N C E M E N T I N I M M U N O A S S A Y BY

M O D U L A T I O N O F C H E M I C A L C A T A L Y S I S

Michael E Perlman, Susan Evans assigned to Becton Dickinson and Company

A method for immunoassay for a ligand suspec- ted to be present in a fluid includes use of an en- zyme, a metal ion catalyst for an indicator reaction and a blocked modulator for the