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1. Basic Human Pathology: Neoplasia
2. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 1
3. Neoplasia
4. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 2
5. Neoplasia
6. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 3
7. Neoplasia
8. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 4
9. Histological loss of differentiation
10. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 5
11. Neoplasia
12. Benign neoplasm of thyroid gland – well circumscribed...
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 6
13. Exophytic and Endrophytic Tumor Growth
14. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 7
15. Malignant Tumor of Breast –
16. Neoplasia: Slide 16
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 8
17. Neoplasia: Slide 17
18. Normal cartilage
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 9
19. Neoplasia
20. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 10
21. Neoplasia
22. Main Routes of Tumor Spread
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 11
23. Symptoms from Metastasis
24. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 12
25. Neoplasia: Slide 25
26. Steps to Metastasis of a Primary Neoplasm
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 13
27. Neoplasia
28. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 14
29. Neoplasia
30. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 15
31. Neoplasia
32. Well differentiated squamous cell carcinoma
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 16
33. Poorly differentiated spindle sq cell ca
34. Poorly differentiated spindle sq cell ca
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 17
35. Neoplasia
36. Neoplasia - Staging
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 18
37. Neoplasia
38. Tumor – Nodes - Metastases
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 19
39. Neoplasia
40. Breast Carcinoma in situ – Confined to the Ducts
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 20
41. Neoplasia
42. Neoplasia: Slide 42
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 21
43. Neoplasia
44. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 22
45. Systematic Tumor Nomenclature
46. Classification of Neoplasms
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 23
47. Classification of Neoplasms, cont’d
48. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 24
49. Non-systematic Terms for Prominent Huma Neoplams
50. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 25
51. Neoplasia
52. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 26
53. Neoplasia
54. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 27
55. Action of Oncogenes in Neoplastic Transformation of Cells
56. Action of Oncogenes in Neoplastic Transformation of Cells
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 28
57. Action of Oncogenes in Neoplastic Transformation of Cells
58. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 29
59. Neoplasia
60. Cell Cycle
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 30
61. Neoplasia
62. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 31
63. Neoplasia: Slide 63
64. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 32
65. Neoplasia
66. Neoplasia: Slide 66
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 33
67. Neoplasia
68. Colon Cancer Model of Multistep Carciogenesis
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 34
69. Neoplasia
70. Characterized Heritable Neoplasia Syndromes
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 35
71. Diagram on the Progression of Cancer Growth
72. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 36
73. Neoplasia
74. Neoplasia: Slide 74
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 37
75. Neoplasia
76. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 38
77. Neoplasia
78. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 39
79. Neoplasia: Slide 79
80. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 40
81. Neoplasia
82. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 41
83. Neoplasia
84. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 42
85. Neoplasia
86. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 43
87. Neoplasia
88. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 44
89. Neoplasia
90. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 45
91. Estimated 10 Leading Sites of New Cancer Cases
92. 2006 Estimated US Cancer Cases*
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Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 46
93. 2006 Estimated US Cancer Deaths
94. Cancer Incidence by Age Groups
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 47
95. Percent Distribution of Cancer Cases
96. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 48
97. Neoplasia
98. Characterized Heritable Neoplasia Syndromes
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 49
99. Neoplasia
100. Needle Biopsy / Endoscopic Biopsy
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 50
101. Excisional Biopsy Scalpel /Excisional/Incisional Biopsy R...
102. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 51
103. Brushing an Ulcer
104. Pulmonary Fine Needle Aspiration (FNA)
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 52
105. Neoplasia
106. Neoplasia: Slide 106
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 53
107. Neoplasia
Tufts OpenCourseWare © 2008 Tufts University
Neoplasia
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 54