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    BSN4A (GROUP 2) 29

    X. Drug Study

    Drug Name Dosage Mechanism of

    Action

    Indication Adverse Reaction Contraindication Nursing

    Responsibility

    Generic:

    Clonazepam

    Brand:

    Rivotril

    Classification:

    Anticonvulsant

    Antiepileptic

    Dosage:

    0.5 mg per Tablet

    Frequency:

    OD

    Route:

    Per orem

    Clonazepam exertsits action by binding

    to thebenzodiazepine site

    of the GABA

    receptors, whichcauses an

    enhancement of theelectric effect of

    GABA binding onneurons, resulting in

    an increased influxof chloride ions into

    the neurons. This

    results in aninhibition of synaptictransmission across

    the central nervoussystem.

    (Pharmacology and

    the Nursing Process.4th Ed. 2005. Mosby,

    Inc. USA)

    Periodic legmovements during

    sleep, hypokineticdysarthria, acutemanic episodes,

    multifocal ticdisorders, neuralgias

    Used alone or as

    adjunct in treatmentof Lennox-Gastaut

    syndrome (petit malvariant), akinetic and

    myoclonic seizures;

    may be useful inpatients with absence

    (petit mal) seizures,

    treatment of panic

    disorder with or

    without agoraphobia

    CNS: transient, milddrowsiness initially;

    sedation, depression,lethargy, apathy,fatigue,

    disorientation, anger,hostility, episodes of

    mania andhypomania,

    restlessness, crying,delirium, slurred

    speech, stupor, vividdreams.

    CV: Bradycardia,tachycardia, CVcollapse,

    hypertension,palpitations, edema

    Integ: Urticaria,

    pruritus, rash,dermatitis

    EENT: Visual and

    auditory

    disturbances,diplopia, nystagmus,nasal congestion

    Contraindicated withhypersensitivity to

    benzodiazepines,psychoses, acute

    narrow-angle

    glaucoma, shock,coma, acute

    alcoholicintoxication with

    depression of vitalsigns.

    Use cautiously with

    impaired liver or

    kidney function,debilitation.

    Assessment and

    Drug Effects

    Hypersensitivitytobenzodiazepines;

    psychoses, acutenarrow-angle

    glaucoma, shock,coma, acute

    alcoholicintoxication, liver

    renal impairment

    Monitor addiction-prone patients

    carefully becauseof their

    predisposition to

    habituation anddrug dependence

    Monitor liverfunction and bloodcounts

    periodically inpatients on long

    tern therapy.

    Monitor patientfor therapeutic

    drug levels: 2080 ng/mL.

    http://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Central_nervous_system
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    BSN4A (GROUP 2) 30

    GI: constipation,diarrhea, dry mouth,

    nausea, anorexia,gastric disorders

    GU: Incontinence,

    urinary retention,changes in libido

    Hema:blood

    dyscrasias,agranulocytosis,

    leucopenia

    Other: hiccups,fever, diaphoresis,

    paresthesias,gynecomastia.

    Patient & Family

    Education

    Take drug exactlyas prescribed; do

    not take drugwithout consulting

    health careprovider

    Avoid alcohol,sleep inducing or

    over the counterdrugs

    Report severedizziness,

    weakness,drowsiness that

    persists, rash orskin lesions,

    difficulty voiding,palpitations,

    swelling in theextremities.

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    BSN4A (GROUP 2) 31

    Drug Name Dosage Mechanism of

    Action

    Indication Contraindication Adverse Reaction Nursing

    Responsibility

    Generic:

    Polynerv

    Brand:

    Vitamin B

    Complex

    Classification:

    Vitamins andMinerals

    Dosage:

    500 mg per Tablet

    Frequency:

    OD

    Route:

    Per orem

    A coenzyme thatstimulate metabolic

    function and isneeded for cell

    replication,hematopoiesis, andnucleoprotein and

    myelin synthesis.Vitamins B1, B6and

    B12 (Polynerv) oraldrops is valuable in

    conditions where therequirements for B

    vitamins areincreased as in

    growth, physiologic

    stress, decreasedresistance to

    infection and chronic

    illnesses, metabolicdisorder sand in

    certain diseases ofthe digestive tract

    and nervous system.(Roth, L.S. (2010).

    Mosbys NursingDrug Reference, 23.

    USA: Mosby, Inc)

    Rheumaticpains,

    alcoholism,cardiac

    disorders, lowblood pressure.

    Vitamin B complexshould not be used in

    hypersensitivity toany of the vitamins

    hypersensitive tovitamin B12 or

    cobalt, containing in

    the preparation, aswell as in patients with

    2nd

    or 3rd

    degreearterial hypertension

    CV: peripheralvascular thrombosis,

    heart failure.

    GI: transientdiarrhea.

    Respi:pulmonaryedema.

    Skin: itching,

    transitoryexanthema, urticaria.

    Other: anaphylaxis,

    pain.

    Assessment and

    Drug Effects

    Determinereticulocyte count,

    hct, Vit. B12, iron,folate levels before

    beginning therapy.

    Obtain a sensitivitytest history beforeadministration

    Avoid I.V.administration

    because fastersystemic

    elimination willreduce

    effectiveness ofvitamin.

    Dont give largedoses of vitamin

    B12 routinely; drug

    is lost throughexcretion.

    Protect Vit. B12from light. Dont

    refrigerate orfreeze.

    Monitor patient forhypokalemia for

    first 48 hours, asanemia correct

    http://www.mims.com.ph/Page.aspx?menuid=companionhome&ID=70http://www.mims.com.ph/Page.aspx?menuid=companionhome&ID=70
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    BSN4A (GROUP 2) 32

    itself. Givepotassium

    supplements, asneeded.

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    BSN4A (GROUP 2) 33

    Drug Name Dosage Mechanism of

    Action

    Indication Contraindications Adverse Reaction Nursing

    Responsibilities

    Generic:

    Diphenhydraminehydrochloride

    Brand:

    Benadryl

    Classification:

    Anticholinergic,

    Antiparkinsoniandrug

    Dosage:

    50 mg per capsule

    Frequency:

    ODHS

    Route:

    Per orem

    Competes withhistamine for H1

    receptor site.Antagonizes the

    effect of histamine atH1 receptor sites;does not bind or

    inactivate histamine.Prevents, but doesnt

    reverse, histaminemediated responses

    particularly those ofbronchial tubes, GI

    tract, and bloodvessels

    (Roth, L.S. (2010).

    Mosbys NursingDrug Reference, 23.

    USA: Mosby, Inc)

    Pseudoparkinsonismdrug-induced

    extrapyramidaleffects

    Used to treat anxiety,tension,

    sleeplessness orinvoluntary

    movements due tothe side effects of

    certain psychiatricdrugs

    Contraindicated inpatients with

    hypersensitivity todrug.

    Avoid use in patientstaking MAO

    inhibitors

    Caution in patientswith asthma, COPD,

    cardiac disease orhypertension,

    glaucoma, andgastric or duodenal

    ulcers

    CNS: drowsiness,confusion, insomnia,

    headache, vertigo,sedation, sleepiness,

    nervousness,restlessness

    CV: Palpitations,hypotension,

    tachycardia

    EENT:blurred vision,

    nasalcongestion,

    tinnitus

    GIT: nausea andvomiting, dry mouth,

    constipation,anorexia

    Urogenital: dysurea,

    urine retention,urinary frequency

    Hema: hemolytic

    anemia,

    thrombocytopenia,agranulocytosis

    Assessment and

    Drug Effects

    When taking thesemedications, the

    client needs to haveblood cells counts,renal function,

    hepatic function,and blood pressure

    monitored.

    Assess for allergyPatient & Family

    Education

    Caution the clientthat the

    medication maycause drowsiness,creating

    difficulties orhazards or other

    activities that

    require alertness.

    Tell the client totake themedication with

    food to decreaseGI upset.

    Explain to theclient that arising

    quickly from a

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    BSN4A (GROUP 2) 34

    Respi: thickening ofbronchial secretions

    Skin: Urticaria,

    photosensitivity,rash.

    Other : anaphylactic

    shock

    lying or sittingposition may

    cause orthostatichypotension.

    Explain to theclient that use of

    these drugs inwarm weather

    may increase thelikelihood of

    heatstroke.

    Report difficultyof breathing

    Administer syrupform if patient is

    unable to taketablets

    Warn patient notto take this drugwith any other

    products thatcontain

    diphenhydramine(including topical

    therapy) becauseof increased

    adverse reactions.

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    BSN4A (GROUP 2) 35

    Drug Name Dosage Mechanism of

    Action

    Indication Contraindications Adverse Reaction Nursing

    Responsibility

    Generic:

    Ascorbic Acid

    Brand:

    Nutri Cee

    Classification:

    Vitamins

    DOSAGE:

    500 mg in tabletform

    FREQUENCY:

    OD

    ROUTE:

    Per orem

    Thechemopreventive

    action of vitamin Cis attributed to two of

    its functions. It is awater-soluble chain

    breaking antioxidant.

    As an antioxidant, itscavenges free

    radicals and reactiveoxygen molecules,

    which are producedduring metabolic

    pathways ofdetoxification.

    It also prevents

    formation ofcarcinogens from

    precursor

    compounds.The structure of

    ascorbic acid isreminiscent of

    glucose, from whichit is derived in the

    majority of mammals(Wolters Kluwer,

    2009)

    Increases protectionmechanism of the

    immune system, thussupporting wound

    healing. Necessaryfor wound healingand resistance to

    infection.

    Prevention andtreatment of vitamin

    C deficiency

    Use of sodiumascorbate in patients

    on sodium restriction

    Use of calciumascorbate in patientsreceiving digitalis.

    GI: Nausea,vomiting, heartburn,

    diarrhea, orabdominal cramps

    (high doses).

    Hematologic: Acute

    hemolytic anemia(patients with

    deficiency of G6PD);sickle cell crisis.

    CNS: Headache or

    insomnia (highdoses).

    Urogenital:Urethritis, dysuria,crystalluria,

    hyperoxaluria, orhyperuricemia (high

    doses).

    Other: Mildsoreness at injection

    site; dizziness andtemporary faintness

    with rapid IV

    administration.

    Assessment & Drug

    Effects Lab tests:

    Periodic Hct &

    Hgb, serumelectrolytes.

    Monitor forS&S of acutehemolytic

    anemia, sicklecell crisis.

    Patient & Family

    Education Take large dosesof vitamin C in

    divided amountsbecause the bodyuses only what is

    needed at aparticular time and

    excretes the rest inurine.

    Megadoses caninterfere with

    absorption ofvitamin B12.

    Note: VitaminC increases theabsorption of ironwhen taken at the

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    BSN4A (GROUP 2) 36

    same time as iron-rich foods.

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    BSN4A (GROUP 2) 37

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    BSN4A (GROUP 2) 38

    NURSING CARE PLAN # 2

    Assessment Data Nursing Diagnosis Rationale Expected Outcome Nursing Intervention Justification Evaluation

    Actual/Abnormal

    Cues:

    Difficultyfalling asleep atnight

    Clientsverbalization

    hambal sangdoctor side

    effect na kunosang bulong ko

    Long hours ofsleep at daytime

    (average of 3-5hours)

    Fatigue onawakeningRisk Factors:

    Side effects ofmedications

    Environment History of

    alcoholism

    History ofchronic cigarette

    smoking

    Disturbed sleep

    pattern related to

    excessive daytime

    sleepingsecondary to

    medications as

    evidenced bydifficulty falling

    asleep at night,long hours of sleep

    at daytime andfatigue on

    awakening.

    Definition:

    Disturbed sleeppatternis the state

    in which anindividual

    experiences or isat risk of

    experiencing achange in the

    quantity or quality

    of his or her restpattern that causes

    discomfort or

    Predisposing factors:

    History of substanceabuse

    Precipitating factors:

    History of alcoholism History of chronic

    cigarette smoking

    Environment

    Health care intervention

    Administration ofmedications

    Therapeuticeffects

    Non-therapeuticeffects

    Drowsiness and sleepiness

    during daytime

    Difficulty sleeping at nighttime

    Fatigue upon awakening in

    the morning

    Disturbed sleep pattern

    After 32 hours of

    nurse-clientinteraction, the

    client will be ableto:

    1. Identifypersonal habits

    that disruptsleep pattern.

    1.1Obtain a sleep-wake history

    including historyof sleep problems,

    changes in sleeppatterns, and use of

    medications andstimulants.

    1.2Assess for use ofalcohol orcigarettes prior to

    use of sleepmedication or

    retiring for theevening.

    1.1Assessment ofsleep behavior

    and patterns arean important

    part of anyhealth status

    examination.

    1.2Alcohol andnicotine should

    be avoided for

    several hoursprior to sleep.

    After 32 hours of

    nurse-clientinteraction, the client

    was able to:

    1.Goal met.Recognize that

    before he wasadmitted,

    prohibited drugsused to relax him;

    but now that he isunder treatment,

    the medication he

    is taking causeshim to have sleepdisturbance. He

    verbalized thataccording to the

    doctor, what he isexperiencing is

    one of the sideeffects of his

    medications. Healso added that his

    cravings for drugs

    especially at nightcontribute to hissleep disturbance.

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    BSN4A (GROUP 2) 39

    Strengths:

    Strong spiritualbelief

    Disciplined Good

    interpersonal

    relationship Compliance to

    treatmentregime

    Willingness tochange to

    improve hishealth

    interferes withdesired lifestyle.

    Source:Handbook of

    Nursing Diagnosis13 Ed by Moyet

    Pp 446-449

    Source:Handbook of Nursing

    Diagnosis 13 Ed by Moyetpp 446-449

    2. Verbalize waysthat can help

    promote hissleeping

    pattern.

    2.1 Initiatenon-

    pharmacologicinterventions for

    improved sleepincluding:

    Encourageclient to have

    an increase insunlight

    exposure

    Provideeducational

    interventions topromote

    beneficial sleephygiene

    (Including theimpact of

    substance useon sleep

    quality,keeping regular

    waking andsleeping times,

    avoiding naps,refraining from

    caffeine,impact of

    exercise onsleep and

    environmental

    2.1 Non-pharmacologic

    interventionshave been

    found toimprove sleep

    efficiency andincrease

    satisfaction withsleep pattern

    whiledecreasing

    use ofhypnotics.

    2.Goal met. Statethat he usually

    watches televisionor have a chit-chat

    with hisroommates to help

    him fall asleep andlessen the cravings

    of taking drugs.He added that he

    would sometimeswrite anything or

    read magazinesand play with his

    friends so that hecould divert his

    attention and hewill not get sleepy

    during the day.

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    BSN4A (GROUP 2) 40

    3. Achieveoptimal

    amounts ofsleep as

    evidenced byverbalization of

    feeling restedand improved

    sleepingpattern.

    adjustments topromote sleep)

    Providediversionalactivities to

    providestimulation

    (talking to co-residents, play

    games)

    3.1 Evaluate learningoutcomes using

    patientverbalizations of

    following thetreatment

    recommendationsand experiencing

    enhanced sleep.

    3.1Evaluationserves as an

    assessment ofthe

    effectiveness ofcare and allows

    opportunity foradjustments to

    the plan of care

    Source:

    http://www.pterrywave.

    com/nursing/care%20plans/

    51.aspx

    3.Goal partially met.Verbalize biskan

    makatulug ko saaga..makatulug

    naman ko amat-amat kung

    gabemakapahuway naman ko

    sang maayo kagga amat-amat

    naman dula angsakit sa kalawasan

    ko

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    BSN4A (GROUP 2) 41

    NURSING CARE PLAN # 3

    Assessment Data Nursing Diagnosis Rationale Expected Outcome Nursing Intervention Justification Evaluation

    Risk factors:

    Physical isolation Social isolation Affectionaldeprivation Substance abuseStrengths:

    Extrovertpersonality

    Goodinterpersonal

    relationship

    Beingparticipative and

    active duringgroup sessions

    Good familysupport

    Risk for loneliness

    related to

    therapeutic

    isolation secondaryto substance abuse.

    Definition:

    Risk for LonelinessThe state in which anindividual is at risk

    for experiencingdiscomfort

    associated with adesire or need for

    contact with others.

    Source:

    Handbook ofNursing Diagnosis13 Ed by Moyet

    Predisposing factors:

    GenderPrecipitating factors: Substance abuse Admission to the

    institution

    Physical isolation

    Social isolation

    Impaired socialinteraction

    Affectionaldeprivation

    Risk for loneliness

    Source:

    Handbook of

    Nursing Diagnosis13 Ed by MoyetPp 273-277

    After 32 hours of

    nurse-clientinteraction, the client

    will be able to:

    1. Verbalizefeelings ofloneliness and

    express desire tosocialize more.

    1.1Work with thepatient to identifyfactors and

    behaviors thathave contributed

    to loneliness.

    1.2Help clientidentify feelings

    associated with

    loneliness.

    1.3Spend sufficienttime with the

    patient to allow

    him to expresshis feelings.

    1.4Encourage clientto address his

    needs assertively.

    1.1To beginchanging

    behaviors that

    may havealienated others.

    1.2This lessens theimpact of

    feelings and

    mobilizes energyto counteractthem.

    1.3To establish atrustingrelationship.

    1.4By beingassertive, client

    assumesresponsibility formeeting his

    After 32 hours of

    nurse-clientinteraction, the client

    was able to:

    1. Goal met.Verbalize,Nasubon ko di kay wala

    kami di masyadomay ginahimo,

    lalo na bi kungwala kamo, subo

    gid ya eh! Sadyakung ari kamo di

    kag kung wala na

    kami himo-on galantaw kami tv orga hampang diri

    sa may polan.

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    BSN4A (GROUP 2) 42

    Pp 273-277

    2. Identify peoplewho will likelysupport and

    accept him.

    3.

    Formulate planson how to

    comfortably

    2.1 Inform client

    that assistance isavailable to help

    him expressfeelings of

    loneliness andidentify ways to

    increase socialactivity.

    2.2 Help client curb

    feelings ofloneliness by

    encouraging one-on-one

    interaction withothers who are

    likely to accepthim.

    3.1As clientscomfort level

    improves,

    needs withoutanger or guilt.

    2.1 To bring issue

    into open andhelp client

    understand thatyou want to help

    him.

    2.2 To promote

    feelings ofacceptance and

    support.

    3.1To promote theuse of social

    skills.

    2.Goal met. Statekung daw kasubo na gid, ga

    isturya na lang kosa mga upod ko

    lalo na kay JR kaymigo ko na siya

    di. Dayun gapasalamat man ko

    kay ginadu-aw kodi kag

    ginasuportahan kosang akun amay

    kag iloy kag kungkis-a upod man

    nila ang bata ko.Masadyahan

    naman ko nadayun kay

    maisturya ko silakag makamusta

    man. Gapasalamat man ko

    kay ari kamo dipara may ma

    isturya man ko.

    3.Goal met.Encourage his

    colleagues to join

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    BSN4A (GROUP 2) 43

    interact withpeers and on

    how to continueinvolvement

    with othersthrough

    recreationalactivities or

    social interactiongroups.

    encourage him toattend to group

    activities andsocial functions.

    3.2Refer client andfamily to socialservice agencies,

    mental healthcenter and

    appropriatesupport groups.

    3.2To ensurecontinued careand maintain

    socialinvolvement.

    Source:http://nandanursing

    diagnosis.org/nursing-diagnosis-

    risk-loneliness/

    the morningworship and join

    the activities leadby the students.

    Also, he alwaystry to play with

    his colleagues soas to maintain his

    good interpersonalrelationship with

    them.

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    BSN4A (GROUP 2) 44

    X. Drug Study

    Drug Name Dosage Mechanism of

    Action

    Indication Adverse Reaction Contraindication Nursing

    Responsibility

    Generic:

    Clonazepam

    Brand:

    Rivotril

    Classification:

    Anticonvulsant

    Antiepileptic

    Dosage:

    0.5 mg per Tablet

    Frequency:

    OD

    Route:

    Per orem

    Clonazepam exertsits action by binding

    to the

    benzodiazepine siteof the GABA

    receptors, whichcauses an

    enhancement of theelectric effect of

    GABA binding onneurons, resulting in

    an increased influxof chloride ions into

    the neurons. This

    results in aninhibition of synaptictransmission across

    the central nervoussystem.

    (Pharmacology and

    the Nursing Process.4th Ed. 2005. Mosby,

    Inc. USA)

    Periodic legmovements during

    sleep, hypokinetic

    dysarthria, acutemanic episodes,

    multifocal ticdisorders, neuralgias

    Used alone or as

    adjunct in treatmentof Lennox-Gastaut

    syndrome (petit malvariant), akinetic and

    myoclonic seizures;

    may be useful inpatients with absence(petit mal) seizures,

    treatment of panicdisorder with or

    without agoraphobia

    CNS: transient, milddrowsiness initially;

    sedation, depression,

    lethargy, apathy,fatigue,

    disorientation, anger,hostility, episodes of

    mania andhypomania,

    restlessness, crying,delirium, slurred

    speech, stupor, vividdreams.

    CV: Bradycardia,tachycardia, CVcollapse,

    hypertension,palpitations, edema

    Integ: Urticaria,

    pruritus, rash,dermatitis

    EENT: Visual and

    auditory

    disturbances,diplopia, nystagmus,nasal congestion

    Contraindicated withhypersensitivity to

    benzodiazepines,

    psychoses, acutenarrow-angle

    glaucoma, shock,coma, acute

    alcoholicintoxication with

    depression of vitalsigns.

    Use cautiously with

    impaired liver or

    kidney function,debilitation.

    Assessment and

    Drug Effects

    Hypersensitivityto

    benzodiazepines;

    psychoses, acutenarrow-angle

    glaucoma, shock,coma, acute

    alcoholicintoxication, liver

    renal impairment

    Monitor addiction-prone patients

    carefully becauseof theirpredisposition to

    habituation anddrug dependence

    Monitor liverfunction and bloodcounts

    periodically inpatients on long

    tern therapy.

    Monitor patientfor therapeuticdrug levels: 2080 ng/mL.

    http://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Central_nervous_systemhttp://en.wikipedia.org/wiki/Central_nervous_system
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    BSN4A (GROUP 2) 45

    GI: constipation,diarrhea, dry mouth,

    nausea, anorexia,gastric disorders

    GU: Incontinence,

    urinary retention,changes in libido

    Hema:blood

    dyscrasias,agranulocytosis,

    leucopenia

    Other: hiccups,fever, diaphoresis,

    paresthesias,gynecomastia.

    Patient & Family

    Education

    Take drug exactlyas prescribed; do

    not take drugwithout consulting

    health careprovider

    Avoid alcohol,sleep inducing or

    over the counterdrugs

    Report severedizziness,

    weakness,drowsiness that

    persists, rash orskin lesions,

    difficulty voiding,palpitations,

    swelling in theextremities.

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    BSN4A (GROUP 2) 46

    Drug Name Dosage Mechanism of

    Action

    Indication Contraindication Adverse Reaction Nursing

    Responsibility

    Generic:

    Polynerv

    Brand:

    Vitamin B

    Complex

    Classification:

    Vitamins andMinerals

    Dosage:

    500 mg per Tablet

    Frequency:

    OD

    Route:

    Per orem

    A coenzyme thatstimulate metabolic

    function and isneeded for cell

    replication,

    hematopoiesis, andnucleoprotein and

    myelin synthesis.Vitamins B1, B6and

    B12 (Polynerv) oraldrops is valuable in

    conditions where therequirements for B

    vitamins areincreased as in

    growth, physiologicstress, decreased

    resistance toinfection and chronic

    illnesses, metabolicdisorder sand in

    certain diseases ofthe digestive tract

    and nervous system.(Roth, L.S. (2010).

    Mosbys NursingDrug Reference, 23.

    USA: Mosby, Inc)

    Rheumaticpains,

    alcoholism,cardiac

    disorders, low

    blood pressure.

    Vitamin B complexshould not be used in

    hypersensitivity toany of the vitamins

    hypersensitive to

    vitamin B12 orcobalt, containing in

    the preparation, aswell as in patients with

    2nd

    or 3rd

    degreearterial hypertension

    CV: peripheralvascular thrombosis,

    heart failure.

    GI: transient

    diarrhea.

    Respi:pulmonaryedema.

    Skin: itching,

    transitoryexanthema, urticaria.

    Other: anaphylaxis,

    pain.

    Assessment and

    Drug Effects

    Determinereticulocyte count,hct, Vit. B12, iron,

    folate levels beforebeginning therapy.

    Obtain a sensitivitytest history beforeadministration

    Avoid I.V.administration

    because fastersystemic

    elimination willreduce

    effectiveness ofvitamin.

    Dont give largedoses of vitamin

    B12 routinely; drug

    is lost throughexcretion.

    Protect Vit. B12from light. Dont

    refrigerate orfreeze.

    Monitor patient forhypokalemia forfirst 48 hours, asanemia correct

    http://www.mims.com.ph/Page.aspx?menuid=companionhome&ID=70http://www.mims.com.ph/Page.aspx?menuid=companionhome&ID=70
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    BSN4A (GROUP 2) 47

    itself. Givepotassium

    supplements, asneeded.

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    BSN4A (GROUP 2) 48

    Drug Name Dosage Mechanism of

    Action

    Indication Contraindications Adverse Reaction Nursing

    Responsibilities

    Generic:

    Diphenhydraminehydrochloride

    Brand:

    Benadryl

    Classification:

    Anticholinergic,

    Antiparkinsoniandrug

    Dosage:

    50 mg per capsule

    Frequency:

    ODHS

    Route:

    Per orem

    Competes withhistamine for H1

    receptor site.Antagonizes the

    effect of histamine at

    H1 receptor sites;does not bind or

    inactivate histamine.Prevents, but doesnt

    reverse, histaminemediated responses

    particularly those ofbronchial tubes, GI

    tract, and bloodvessels

    (Roth, L.S. (2010).Mosbys Nursing

    Drug Reference, 23.USA: Mosby, Inc)

    Pseudoparkinsonismdrug-induced

    extrapyramidaleffects

    Used to treat anxiety,tension,

    sleeplessness orinvoluntary

    movements due tothe side effects of

    certain psychiatricdrugs

    Contraindicated inpatients with

    hypersensitivity todrug.

    Avoid use in patientstaking MAO

    inhibitors

    Caution in patientswith asthma, COPD,

    cardiac disease orhypertension,

    glaucoma, andgastric or duodenal

    ulcers

    CNS: drowsiness,confusion, insomnia,

    headache, vertigo,sedation, sleepiness,

    nervousness,

    restlessness

    CV: Palpitations,hypotension,

    tachycardia

    EENT:blurred vision,

    nasalcongestion,

    tinnitus

    GIT: nausea andvomiting, dry mouth,

    constipation,anorexia

    Urogenital: dysurea,

    urine retention,urinary frequency

    Hema: hemolytic

    anemia,thrombocytopenia,

    agranulocytosis

    Assessment and

    Drug Effects

    When taking thesemedications, theclient needs to have

    blood cells counts,renal function,

    hepatic function,and blood pressure

    monitored.

    Assess for allergyPatient & Family

    Education

    Caution the clientthat themedication may

    cause drowsiness,creating

    difficulties orhazards or other

    activities that

    require alertness.

    Tell the client totake themedication with

    food to decreaseGI upset.

    Explain to theclient that arising

    quickly from a

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    BSN4A (GROUP 2) 49

    Respi: thickening ofbronchial secretions

    Skin: Urticaria,

    photosensitivity,rash.

    Other : anaphylacticshock

    lying or sittingposition may

    cause orthostatichypotension.

    Explain to theclient that use of

    these drugs in

    warm weathermay increase thelikelihood of

    heatstroke.

    Report difficultyof breathing

    Administer syrupform if patient is

    unable to taketablets

    Warn patient notto take this drugwith any other

    products thatcontain

    diphenhydramine(including topical

    therapy) becauseof increased

    adverse reactions.

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    BSN4A (GROUP 2) 50

    Drug Name Dosage Mechanism of

    Action

    Indication Contraindications Adverse Reaction Nursing

    Responsibility

    Generic:

    Ascorbic Acid

    Brand:

    Nutri Cee

    Classification:

    Vitamins

    DOSAGE:

    500 mg in tabletform

    FREQUENCY:

    OD

    ROUTE:

    Per orem

    Thechemopreventive

    action of vitamin Cis attributed to two of

    its functions. It is a

    water-soluble chainbreaking antioxidant.

    As an antioxidant, itscavenges free

    radicals and reactiveoxygen molecules,

    which are producedduring metabolic

    pathways ofdetoxification.

    It also preventsformation of

    carcinogens fromprecursor

    compounds.The structure of

    ascorbic acid isreminiscent of

    glucose, from whichit is derived in the

    majority of mammals(Wolters Kluwer,

    2009)

    Increases protectionmechanism of the

    immune system, thussupporting wound

    healing. Necessary

    for wound healingand resistance to

    infection.

    Prevention andtreatment of vitamin

    C deficiency

    Use of sodiumascorbate in patients

    on sodium restriction

    Use of calcium

    ascorbate in patientsreceiving digitalis.

    GI: Nausea,vomiting, heartburn,

    diarrhea, orabdominal cramps

    (high doses).

    Hematologic: Acute

    hemolytic anemia(patients with

    deficiency of G6PD);sickle cell crisis.

    CNS: Headache or

    insomnia (highdoses).

    Urogenital:Urethritis, dysuria,crystalluria,

    hyperoxaluria, orhyperuricemia (high

    doses).

    Other: Mildsoreness at injection

    site; dizziness andtemporary faintness

    with rapid IVadministration.

    Assessment & Drug

    Effects Lab tests:

    Periodic Hct &

    Hgb, serum

    electrolytes. Monitor for

    S&S of acutehemolytic

    anemia, sicklecell crisis.

    Patient & Family

    Education Take large dosesof vitamin C individed amounts

    because the bodyuses only what is

    needed at aparticular time and

    excretes the rest inurine.

    Megadoses caninterfere with

    absorption ofvitamin B12.

    Note: VitaminC increases the

    absorption of ironwhen taken at the

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    BSN4A (GROUP 2) 51

    same time as iron-rich foods.