Giving Effective Presentations, Oct. 2016

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  • GivingEffectivePresentations

    ClausO.WilkeTheUniversityofTexasatAus9n

  • Whycareaboutpresenta9ons?

  • WhatIwillcover

    1. Howtopresentanengagingstory2. Designingslides:TheAsser9onEvidencetemplate3. Claus'petpeevesaboutpresenta9ons

  • 1.Presentinganengagingstory:

    TheOnionmodel

  • Let'sstartwithanexample.Abadone.

  • Ketogenic diet as supporting treatment option in glioblastoma multiformae

  • Ketogenic diet as supporting treatment option in glioblastoma multiformae

    Onaketogenicdiet,theliverproducesketonebodies,inpar9cular-hydroxybuturate(BHB)

  • Ketogenic diet as supporting treatment option in glioblastoma multiformae

    BHBcancrosstheblood-brainbarrierandserveasanalterna9vefuelforbraincells,replacingglucose

  • Ketogenic diet as supporting treatment option in glioblastoma multiformae

    Adietisketogenicwhencarbohydrateintakefallsbelow20-50gram/daywhilefatcomprises~80%ofcaloricintake

  • Ketogenic diet as supporting treatment option in glioblastoma multiformae

    Glioblastomamul9formae(GBM)needsglucoseforgrowth,andseemsinhibitedbythepresenceofBHB

  • Ketogenic diet as supporting treatment option in glioblastoma multiformae

    SeveralclinicaltrialsarecurrentlyongoingtodeterminewhetherketogenicdietscansloworinhibitGBMgrowth

  • Didthisgetyouexcitedaboutketogenicdiets?

  • Why eating eggs and bacon may cure brain cancer

  • Why eating eggs and bacon may cure brain cancer

    Canceristheleadingcauseofdeathindevelopedcountries

  • Why eating eggs and bacon may cure brain cancer

    Despitemedicaladvances,mostcancertreatmentsaregruesomeyetonlymoderatelysuccessful

  • Why eating eggs and bacon may cure brain cancer

    Ifwecouldpreventortreatcancerbyasimplechangeindiet,thatwouldbeawesome

  • Why eating eggs and bacon may cure brain cancer

    Increasingevidencelinkscancertohigh-carbohydratediets(inpar9cularsugarandstarches)

  • Why eating eggs and bacon may cure brain cancer

    Ea9ngahigh-fat,low-carbdiet(liketheAtkinsdiet)maystarvetumorsofnecessaryglucose

  • Why eating eggs and bacon may cure brain cancer

    Ini9altrialswithbrain-cancerpa9entshavebeenpromising,andfurthertrialsareongoing

  • Didthisgetyoumoreexcited?

  • TheOnionmodel

  • TheOnionmodel

    Why?

    Thebigpicture:whyarewedoingthis,andwhydoesitma\er?

  • TheOnionmodel

    Why?

    What?

    Relevantbackgroundfacts&

    Whatwasdone?

  • TheOnionmodel

    Why?

    What?

    How?

    Minutedetailsofhowexactlytheworkwasdone

  • TheOnionmodel

    Why?

    What?

    How?

    Minutedetailsofhowexactlytheworkwasdone

    Alwaysgofromtheoutsidein

  • Formaximumimpact,useapproximately

    equalamountsoftimeforeachlayer

    Why? ~30%oftalk

    What? ~30%oftalk

    How? ~30%oftalk(atmost)

  • Let'splacethecontentsofthedietslidesintotheonionframework

  • Ketogenic diet as supporting treatment option in glioblastoma multiformae

    Onaketogenicdiet,theliverproducesketonebodies,inpar9cular-hydroxybuturate(BHB)

    BHBcancrosstheblood-brainbarrierandserveasanalterna9vefuelforbraincells,replacingglucose

    Adietisketogenicwhencarbohydrateintakefallsbelow20-50gram/daywhilefatcomprises~80%ofcaloricintake

    Glioblastomamul9formae(GBM)needsglucoseforgrowth,andseemsinhibitedbythepresenceofBHB

    SeveralclinicaltrialsarecurrentlyongoingtodeterminewhetherketogenicdietscansloworinhibitGBMgrowth

  • Why eating eggs and bacon may cure brain cancer

    Canceristheleadingcauseofdeathindevelopedcountries

    Despitemedicaladvances,mostcancertreatmentsaregruesomeyetonlymoderatelysuccessful

    Ifwecouldpreventortreatcancerbyasimplechangeindiet,thatwouldbeawesome

    Increasingevidencelinkscancertohigh-carbohydratediets(inpar9cularsugarandstarches)

    Ea9ngahigh-fat,low-carbdiet(liketheAtkinsdiet)maystarvetumorsofnecessaryglucose

    Ini9altrialswithbrain-cancerpa9entshavebeenpromising,andfurthertrialsareongoing

  • 2.Designingslides:

    TheAssertionEvidencetemplate

  • Thetitleoftheslidemakesanassertion

    Theslidebodyprovidestheevidencetosupporttheasser9on

  • Examples

  • Sequencingcostshavedeclined1000-fold

    from2007to2010C

    ost p

    er g

    enom

    e

    Year

    Sep. 2007: $10,000,000

    Sep. 2010: $10,000

    Source: genome.gov/sequencingcosts

  • Violentcrimeisatanall-timelowH

    omic

    ides

    /10

    0,00

    0 A

    mer

    ican

    s

    Year Source: http://blogs.berkeley.edu/2010/06/16/a-crime-puzzle-violent-crime-declines-in-america/

  • M&Mscomeinmanyfuncolors

  • 3.Claus'petpeevesabout

    presentations

  • Howtoruinatalkandputyour

    audiencetosleepinoneslide

    ClausO.WilkeTheUniversityofTexasatAus9n

  • Overview

    Introduc9on Background Methods Results Conclusions

  • Overview

    Introduc9on Background Methods Results Conclusions

    Never!

  • GivingEffectivePresentations

    ClausO.WilkeTheUniversityofTexasatAus9n

  • Whycareaboutpresenta9ons?

  • WhatIwillcover

    1. Howtopresentanengagingstory2. Designingslides:TheAsser9onEvidencetemplate3. Claus'petpeevesaboutpresenta9ons

  • Claus'1stlawofpresenta9ons

  • Claus'1stlawofpresentations:

    Alltextonslidesneedstobereadaloud

    WhileIgenerallyprefergraphicalvisualiza9ons,insomecasestextispreferred.Forexample,summaryslidesoaenrequiresomeamountoftext.Textisfineaslongasyoureaditwordforword.Ifyoustartparaphrasingortalkingoveratext-heavyslide,however,youraudiencewillgetconfused.Theycannotatthesame9mereadthetextandlistentoyou.Someaudiencememberswillreadthetextandstoplistening.Otherswilllistenbutnotread.Allwillworrythattheymadethewrongchoiceandmissedsomethingimportant.

  • Nowanexampleofhownottodoit

  • Nowanexampleofhownottodoit.

    Thisslideisfulloftext.Likely,noneofthetextma\ers,butyoucan'tknowforsureunlessyoureaditall.Butifyouwanttoreadit,youcan'tlistentomeblatheringonaboutsomethingcompletelydifferent.Thatisbecausehumanscannotprocesstwoseparatecontentstreams(visualandoral)atthesame9me.Nextweek'swinninglo\erynumberswillbe5,13,28,33,34,36,41.IknowbecauseI'ma9metravelerfromthefuture.

  • Whichstorylinewereyouabletofollow?

  • Important:The1stlawalsoappliestoslideswithgraphs!

  • Violentcrimeisatanall-timelowH

    omic

    ides

    /10

    0,00

    0 A

    mer

    ican

    s

    Year Source: http://blogs.berkeley.edu/2010/06/16/a-crime-puzzle-violent-crime-declines-in-america/

  • Asmuchaspossible,avoidbulletpoints

  • The Department in numbers

    We have 36 faculty members Annual grant funding: $5M

    Funding agencies: NSF, NIH, ARO, ONR, DARPA, DTRA, USDA

    Our faculty members supervise 112 graduate students 69 EEB, 23 Plant Biology, 10 CMB, 10 other

    20% of our graduate students receive external fellowships 14 NSF GRFP, 1 NIH F31, 10 other

  • The Department in numbers

    36 faculty members

    112 graduate students

    69 EEB 23 PB 10 CMB 10 Other

    20% students on external fellowships

    14 NSF GRFP 1 NIH F31 10 Other

    $5M annual grant funding

    NSF, NIH, ARO, ONR, DARPA, DTRA, USDA

  • Usediagramsinsteadoftext

  • Analysispipeline

    Kerretal.,J.Virol.2015

  • Builduptocomplex,many-facetedgraphs

  • Bindingtoancestordeclinesrapidlyinthe

    controlscenario

    Kachrooetal.,Science2015

  • Bindingtoancestordeclinesrapidlyinthe

    controlscenario,butnotinWTscenario

    Kachrooetal.,Science2015

  • Evenwithsubstantialdivergenceininterface

    sites,evolvedproteinsbindancestors

    Kachrooetal.,Science2015

    divergenceininterfacesites

    divergenceinnon-interfacesites

  • Paya\en9ontoyourbodylanguage

  • Slidebackgrounds:Whiteordark?

  • Advantagesofwhitebackgrounds

    Easiertoworkwith(figures!) LookOkevenifprojectorisweak

  • Advantagesofdarkbackgrounds

    Moreelegant Easierontheeye Goodwithphotos

    SassodellaCroce,ValBadia,Italy

  • Butpleases9cktoonestyle,whiteorblack

  • Toavoidvisuallyshockingyouraudience

  • Summary

    Tellastory Leadfromthewhy,thencoverthewhatandlimitthehow

    Startthetalkstrong,forexamplewithaninteres9nganecdote

    Usetheasser9onevidencetemplate Don'tstartyourtalkwithaboringoverviewslide Whenyourslidescontaintext,readitout