JARINGANISYARAT:THECELLULARcogwheelsDASARneuroplaststas JANG!A "ANJANG #aru$%arun&peneltan'e(ala)pato*solog(anpengo%atangangguan )oo(telah %ergera'(ar +o'us pa(aneurotrans)ter (anreseptor per)u'aan seluntu'casca(essn,alntraseluler- .ult'o)ponen&/alur sn,alseluler%erntera's( %er%aga tng'atan& sehngga)e)%entu'/arngansn,al,ang'o)ple's,ang)e)ung'n'an sel untu' )ener)a& proses& (an )enanggap n+or)as 012$345- Jarngan n )e)+asltas ntegras sn,al ( %e%erapa s'ala wa'tu& generas output ,ang %er%e(atergantungpa(a 'e'uatan)asu'an(an (uras&(an )engatur ru)t u)pan$)a/u (an loop u)pan %al' 012 $ 345- .engngat peran luas (an pentng )ere'a(ala)ntegras(an*ne$tunng(arproses *sologs& t(a'lah )engheran'an%ahwa'elanan pa(a/alur sn,al'n telah ((ent*'as(ala)%er%agapen,a't )anusa06&36&375-Selantu&/alur sn,al)erupa'antargetuta)a %agse/u)lah hor)on&ter)asu' glu'o'ort'o(&hor)ontro(&(an stero(gona(06&365-E+e'%o')a )ung'n )e)an'an peran(ala))e(as)an+estas 'lnstertentu peru%ahan tng'at hor)on (ala) )ata pela/aran gangguan )oo( 0)saln,a onset serng gangguan %polar pa(a )asa pu%ertas& )e)cu epso(e (ala) pero(epostpartu)&hu%unganantara(epres(an%ersepe(a%erpotens cepat(enganh,poth,ro(s)&(an)e)cuepso(ea+e't+(ala) )enanggapglu'o'ort'o(e'sogen5- Jarngan sn,al ,ang 'o)ple's )ung'n sangat pentng (ala) SS"& ( )ana )ere'a)en)%ang(an)engntegras'ansn,alsara+,ang%eraga)(an 'e)u(an)engr)'an sn,alnterntegras'ee+e'tor&sehngga )e)%entu'(asar (ar/arnganpengolahann+or)as'o)ple's012$345- Tnggn,a tng'at'o)ple'stas,ang (hasl'an oleh/arngansn,aln )ung'n)en/a( salah satu)e'ans)e ()ananeuron)e)peroleh 8e's%ltas untu' )enghasl'an %er%aga respon ,ang (a)at (ala) sste) sara+-Jalurnsehngga(ragu'anlagterl%at (ala))engatur%eraga) +ungs$+ungs9egetat+sepertsuasanahat&na+su)a'an(anter/aga(an 'arena tu)ung'n terl%at(ala) pato*solog#D- !ta se'arang %eralh 'e (s'us tentang%u't langsung(an t(a' langsung)en(u'ungperan 'elanan pa(a/alur sn,al(ala)pato*solog(an pengo%atan#D- TheGs:cA.")enghasl'an/alur sn,al #e%erapala%oratoru)n(epen(ense'arangtelah )elapor'an'elanan pa(aGprotensu%unt(#D031&335-Stu(ota' post)orte)telah )elapor'anpenng'atan'a(arprotenGst)ulas0G;s5(serta (engan penng'atanpasca$reseptor (rangsanga(enlat s'lase0AC5 a't9tas (#D 033&3
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JARINGAN ISYARAT

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JARINGANISYARAT:THECELLULARcogwheelsDASARneuroplaststas JANG!A "ANJANG #aru$%arun&peneltan'e(ala)pato*solog(anpengo%atangangguan )oo(telah %ergera'(ar +o'us pa(aneurotrans)ter (anreseptor per)u'aan seluntu'casca(essn,alntraseluler- .ult'o)ponen&/alur sn,alseluler%erntera's( %er%aga tng'atan& sehngga)e)%entu'/arngansn,al,ang'o)ple's,ang)e)ung'n'an sel untu' )ener)a& proses& (an )enanggap n+or)as 012$345- Jarngan n )e)+asltas ntegras sn,al ( %e%erapa s'ala wa'tu& generas output ,ang %er%e(atergantungpa(a 'e'uatan)asu'an(an (uras&(an )engatur ru)t u)pan$)a/u (an loop u)pan %al' 012 $ 345- .engngat peran luas (an pentng )ere'a(ala)ntegras(an*ne$tunng(arproses *sologs& t(a'lah )engheran'an%ahwa'elanan pa(a/alur sn,al'n telah ((ent*'as(ala)%er%agapen,a't )anusa06&36&375-Selantu&/alur sn,al)erupa'antargetuta)a %agse/u)lah hor)on&ter)asu' glu'o'ort'o(&hor)ontro(&(an stero(gona(06&365-E+e'%o')a )ung'n )e)an'an peran(ala))e(as)an+estas 'lnstertentu peru%ahan tng'at hor)on (ala) )ata pela/aran gangguan )oo( 0)saln,a onset serng gangguan %polar pa(a )asa pu%ertas& )e)cu epso(e (ala) pero(epostpartu)&hu%unganantara(epres(an%ersepe(a%erpotens cepat(enganh,poth,ro(s)&(an)e)cuepso(ea+e't+(ala) )enanggapglu'o'ort'o(e'sogen5- Jarngan sn,al ,ang 'o)ple's )ung'n sangat pentng (ala) SS"& ( )ana )ere'a)en)%ang(an)engntegras'ansn,alsara+,ang%eraga)(an 'e)u(an)engr)'an sn,alnterntegras'ee+e'tor&sehngga )e)%entu'(asar (ar/arnganpengolahann+or)as'o)ple's012$345- Tnggn,a tng'at'o)ple'stas,ang (hasl'an oleh/arngansn,aln )ung'n)en/a( salah satu)e'ans)e ()ananeuron)e)peroleh 8e's%ltas untu' )enghasl'an %er%aga respon ,ang (a)at (ala) sste) sara+-Jalurnsehngga(ragu'anlagterl%at (ala))engatur%eraga) +ungs$+ungs9egetat+sepertsuasanahat&na+su)a'an(anter/aga(an 'arena tu)ung'n terl%at(ala) pato*solog#D- !ta se'arang %eralh 'e (s'us tentang%u't langsung(an t(a' langsung)en(u'ungperan 'elanan pa(a/alur sn,al(ala)pato*solog(an pengo%atan#D- TheGs:cA.")enghasl'an/alur sn,al #e%erapala%oratoru)n(epen(ense'arangtelah )elapor'an'elanan pa(aGprotensu%unt(#D031&335-Stu(ota' post)orte)telah )elapor'anpenng'atan'a(arprotenGst)ulas0G;s5(serta (engan penng'atanpasca$reseptor (rangsanga(enlat s'lase0AC5 a't9tas (#D 033&3
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